Kiki D. Chang, MD | UW Psychiatry Grand Rounds

*** UPDATE: THIS EVENT HAS BEEN CANCELED DUE TO COVID-19 ***

Pediatric Bipolar Disorder: Clues for Early Identification and Prevention

*** Part of the Briskey Family Bipolar Lecture Series ***

Learning objectives:

1. Accurately understand the early presentations of bipolar disorders in youth.
2. Consider alternate diagnoses for youth with irritability and mood difficulties
3. Discuss approaches to identifying and treating youth at high risk for bipolar disorder

Talk Description:

Bipolar disorder (BD) is a chronic, debilitating illness with a lifetime worldwide prevalence of 2.4% and more disability-adjusted life-years lost than major neurological conditions or cancer.  Children with BD have a more severe course of illness with high relapse, recurrence, psychosocial impairment, substance use, and suicide at twice the rate of attempted suicides when compared to individuals with unipolar depression. Identification and recognition of symptoms that predate BD in youth would aid in early intervention and prevention efforts.  This presentation will discuss the clinical presentation of early and fully developed BD in youth, and discuss early intervention efforts so far to treat youth with early forms of BD to prevent development of full BD in their lifetime.

Kiki D. Chang, MD is a Psychiatrist in private practice in Palo Alto, CA. He is a former Professor of Psychiatry and Behavioral Sciences at the Stanford University School of Medicine, Division of Child Psychiatry. He is also former Director of the Pediatric Bipolar Disorders Clinic, where he specialized in pediatric psychopharmacology and treatment of depression and bipolar disorder in children and adolescents. Dr. Chang also previously directed the Pediatric Psychopharmacology and Advanced Pediatric Psychopharmacology courses at Stanford.

Dr. Chang graduated cum laude from Princeton University and received his M.D. from the Tufts University School of Medicine. He completed his general psychiatry residency at the University of Cincinnati and his child psychiatry fellowship at Stanford University. After a postdoctoral research fellowship, Dr. Chang joined the Stanford faculty in 1999.

Dr. Chang is the recipient of the Eli Lilly Pilot Research Award from the American Academy of Child and Adolescent Psychiatry, the Klingenstein Third Generation Foundation Fellowship in Child and Adolescent Depression, and the 2003 American Psychiatric Association/AstraZeneca Young Minds in Psychiatry Award. He has been the recipient of two NARSAD Young Investigator Awards and has received a 5-year Career Development Award from the National Institutes of Health.

As Director of the Pediatric Bipolar Disorders Program, Dr. Chang conducts research into various facets of bipolar disorder. He is currently conducting phenomenologic, biologic, pharmacologic, and genetic studies of bipolar disorder in adults and children. These studies include brain imaging (MRI, MRS, fMRI) and medication trials. He is particularly interested in detecting prodromal bipolar disorder in children who might then be treated to prevent the development of full bipolar disorder. To do this, he has been studying children of parents with bipolar disorder who are at high risk for developing the disorder themselves.

Dr. Chang is the author of numerous papers and book chapters regarding bipolar disorder and pediatric psychopharmacology and has presented widely at national and international scientific conferences and meetings.

Additional Information about Kiki Chang, MD:

CV: Kiki Chang, MD

https://www.kikichangmd.com/ 

https://www.gmeded.com/faculty/kiki-d-chang-md

PBS Interview:
https://www.pbs.org/wgbh/pages/frontline/medicatedchild/interviews/chang.html

Reading List: 

1. Family-focused Therapy for Symptomatic Youths at High Risk for Bipolar Disorder
2. A Pharmacologic Algorithm for Youth Who Are at High Risk for Bipolar Disorder

Accreditation Statement

In support of improving patient care, the University of Wisconsin-Madison ICEP is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Designation Statement:

The University of Wisconsin-Madison ICEP designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. The University of Wisconsin–Madison ICEP, as a member of the University Professional & Continuing Education Association (UPCEA), authorizes this program for 0.1 CEUs or 1.0 hour.