13th annual Greenfield Memorial Lecture:
“Gender Differences in Substance Use Disorders”
Kathleen T. Brady, MD, PhD
Distinguished University Professor
Director, South Carolina Clinical and Translational Research Institute
Medical University of South Carolina
Friday September 20, 2024
12:00-1:15pm, followed by reception
*** light refreshments will be served ***
WisPIC Commons Room
6001 Research Park Blvd
RSVP/REGISTER TO ATTEND
Talk Details:
This presentation will provide an overview of sex/gender differences in the biology, epidemiology and treatment of substance use disorders (SUDs). There are biological sex differences present across an array of systems, including brain structure and function, endocrine function, and metabolic function which are involved in SUDs. Gender (i.e., environmentally and socioculturally defined roles for men and women) also influences the initiation and course of substance use and SUDs. There are also gender differences in psychiatric comorbidity with SUDs and response to some medications. These differences have implications for gender-specific treatments which will be discussed.
Learning Objectives
- Upon completion of this educational activity, individuals will be able to describe gender differences in a variety of substance use disorders
- Upon completion of this educational activity, individuals will be able to describe gender differences in response to medications used to treat substance use disorders
- Upon completion of this educational activity, individuals will be able to discuss elements of substance use disorders treatment programs that are essential for optimal outcomes for women.
- Upon completion of this educational activity, members of the healthcare team will be able to improve their treatment of women with substance use disorders.
About the Speaker:
Dr. Brady is an experienced clinical and translational researcher and has been conducting scientific investigations and clinical work in the field of addictions and psychiatric disorders for over 30 years. Her research focuses on pharmacotherapy of substance use disorders, comorbidity of psychiatric disorders and addictions (e.g., posttraumatic stress disorder and bipolar disorder), gender differences and women’s issues in addictions, and the neurobiologic connections between stress and addictions. She has received numerous federal research grants and has published over 400 peer-reviewed journal articles and co-edited 10 books. She is the Principal Investigator of MUSC’s Clinical and Translational Science Award (CTSA), Principal Investigator of the Southern Consortium Node of the NIDA-funded Clinical Trials Network and Director of MUSC’s Women’s Research Center. Her dedication to furthering research careers has attracted a number of junior investigators and clinicians. She is the former Vice President for Research at the Medical University of South Carolina. She has served at the President of the Association for Medical Education and Research in Substance Use Disorders (AMERSA), the American Academy of Addiction Psychiatry (AAAP) and is the immediate past president of International Society of Addiction Medicine (ISAM).
Reading List:
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Holzhauer CG, Cucciare M, Epstein E. (November, 2020). Sex and Gender Effects in Recovery From Alcohol Use Disorder. Alcohol Research, Current Reviews. PMCID: PMC7668196
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Martina, E.L., Neelonb, B., Brady, K.T., Guille, C., Baker, N.L., Ramakrishnanb, V., Gray, K.M., Saladin, M.E., McRae-Clark, A.L. (March 2023). Differential prevalence of Adverse Childhood Experiences (ACEs) by gender and substance used in clinical studies of cannabis, cocaine, opioid, and tobacco use disorders. American Journal of Drug and Alcohol Abuse.
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Ward MK, Guille C, Jafry A, Gwanzura T, Pryce K, Lewis P, Brady KT. (Aug 2024) Digital health interventions to support women with opioid use disorder: A scoping review. Drug Alcohol Depend. doi:10.1016/j.drugalcdep.2024.111352. Epub 2024 Jun 2. PMID: 38861765.