Charles B. Nemeroff, MD, PhD | UW Psychiatry Grand Rounds

Prediction of Disease Vulnerability and Treatment Response in Mood Disorders and PTSD: Personalized Medicine in Psychiatry

FRIDAY SEPT 13 | 12:00pm
WisPIC Commons Room 1616
6001 Research Park Blvd

Charles B. Nemeroff, MD, PhD
Chair and Professor of Psychiatry
Director, Institute for Early Childhood Adversity Research
University of Texas at Austin – Dell Medical School

Learning Objectives

• To understand the principles of personalized medicine as applied to mood and anxiety disorders.
• To understand the role of Genome Wide Association Studies (GWAS), candidate gene approaches, transcriptomics, epigenetics, and proteomics in predicting disease treatment response in mood and anxiety disorders.
• To understand the potential for functional brain imaging for predicting treatment response in mood and anxiety disorders.
• To understand the role of gene-environment interactions, particularly early life trauma, in predicting treatment response in mood disorders.

Charles B. Nemeroff, MD, PhD, is a Professor of Psychiatry and Acting Chair of the Department of Psychiatry. He is also Associate Chair of Research, and the Director of the Institute for of Early Life Adversity Research at Dell Medical School at the University of Texas at Austin.

He received his MD and PhD (Neurobiology) degrees from the University of North Carolina UNC) School of Medicine in Chapel Hill, North Carolina. After psychiatry residency training at UNC and Duke University, he held faculty positions at Duke University and was Chair of the Department of Psychiatry and Behavioral Sciences at Emory University for 18 years before relocating to the University of Miami in 2009.

He has served as President of the American College of Psychiatrists (ACP) and the American College of Neuropsychopharmacology (ACNP) and sits on the Scientific Advisory Board and Board of Directors of the American Foundation for Suicide Prevention (AFSP) and the Anxiety and Depression Association of America

He has received a number of research and education awards including the Kempf Award in Psychobiology, the Samuel Hibbs Award, Research Mentoring Award,Judson Marmot Award and the Vestermark Award from the American Psychiatric Association (APA), the Mood Disorders Award, Bowis Award and Dean Award from the ACP and the Julius Axelrod Award for mentoring from the ACNP. He was elected to the Institute of Medicine (now the National Academy of Medicine) of the National Academy of Sciences in 2002.

He has been named Alumnus of the Year from the University of North Carolina (UNC) and from the UNC Medical School. He received the Doctorate Honoris Causa from Maimonides University in Buenos Aires in 2015.

His research has focused on the pathophysiology of mood and anxiety disorders with a focus on the role of child abuse and neglect as a major risk factor. He has also focused on the role of mood disorders as a risk factor for major medical disorders including heart disease, diabetes and cancer. He has published more than 1100 research reports and reviews.

He has served on the Mental Health Advisory Council of NIMH and the Biomedical Research Council for NASA. He is the co-editor in chief (with Alan F. Schatzberg, MD.) of the Textbook of Psychopharmacology, published by the APA Press, now in its Fifth Edition.

His research is currently supported by grants from the NIH.