Bradley Christian, Ph.D.
Position title: Professor (Tenure Track)
Phone: Development of PET methodologies to investigate neurochemical changes in the brain and studying novel radioligands to characterize neurotransmitter-protein interactions and how they are influenced by development, genes, environment and aging.
- Lab
- Waisman Center Brain Imaging Laboratory
- Lab
- PET Physics
- Recent Publications
- Pub Med
Dr. Christian serves as the Co-Director of the Waisman Center Brain Imaging Laboratory and Director of PET Physics. He is also a mentor to graduate students in the departments of medial physics and neuroscience. His research focuses on developing and translating novel PET radiotracers and methods for the study of human development, neurodegeneration and neuropsychiatric illness, particularly in the realm of intellectual and developmental disabilities (IDDs). This involves using PET methodologies to investigate neurochemical changes in the brain and studying novel radioligands to characterize neurotransmitter-protein interactions and how they are influenced by development, genes, environment and aging. These imaging methods are being applied to investigate the etiologies and mechanisms in Alzheimer’s Disease, Down syndrome, Alexander Disease, affective disorders, schizophrenia and fetal alcohol exposure. He is a member of the Waisman Center Intellectual and Developmental Disabilities Research Core (IDDRC) and serve as Director of the PET service for the UW ADRC.
Publications
- In vivo characterization and quantification of neurofibrillary tau PET radioligand
- Cognitive Decline and Brain Amyloid-β Accumulation across 3-years in Adults with Down Syndrome
- Longitudinal changes in amyloid PET and volumetric MRI in the non-demented Down syndrome population. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring